Rapid Implementation of a Multidisciplinary COVID‐19 Cytokine Storm Syndrome Task Force
نویسندگان
چکیده
منابع مشابه
Dynamics of a Cytokine Storm
Six volunteers experienced severe inflammatory response during the Phase I clinical trial of a monoclonal antibody that was designed to stimulate a regulatory T cell response. Soon after the trial began, each volunteer experienced a "cytokine storm", a dramatic increase in cytokine concentrations. The monoclonal antibody, TGN1412, raised serum concentrations of both pro- and anti-inflammatory c...
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The increasing insight into pathomechanisms of dysregulated host response in several inflammatory diseases led to the implementation of the term "cytokine storm" in the literature more than 20 years ago. Direct toxic effects as well as indirect immunomodulatory mechanisms during cytokine storm have been described and were the basis for the rationale to use several substances and devices in life...
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ژورنال
عنوان ژورنال: ACR Open Rheumatology
سال: 2021
ISSN: 2578-5745,2578-5745
DOI: 10.1002/acr2.11220